FOLR3 Antibody
| Code | Size | Price |
|---|
| PSI-57-159-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Folate receptor gamma, FR-gamma, Folate receptor 3, FOLR3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the folate receptor (FOLR)
family, members of which have a high affinity for folic acid and
for several reduced folic acid derivatives, and mediate delivery of
5-methyltetrahydrofolate to the interior of cells. This gene
includes two polymorphic variants; the shorter one has two base
deletion in the CDS, resulting in a truncated polypeptide, compared
to the longer one. Both protein products are constitutively
secreted in hematopoietic tissues and are potential serum marker
for certain hematopoietic malignancies. The longer protein has a
71% and 79% sequence homology with the FOLR1 and FOLR2 proteins,
respectively.
Background References:
- O'Byrne, M.R., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(8):689-694(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009)
- Franke, B., et al. Birth Defects Res. PartClin. Mol. Teratol. 85(3):216-226(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FOLR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human FOLR3.
NCBI Gene ID #:
2352
NCBI Official Name:
Folate receptor gamma
NCBI Official Symbol:
FOLR3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
P41439
Protein GI Number:
1169723
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P41439
User NOte:
Optimal dilutions for each application to be determined by the researcher.