RFC1 Antibody
| Code | Size | Price |
|---|
| PSI-60-322-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Replication factor C subunit 1, Activator 1 140 kDa subunit, A1 140 kDa subunit, Activator 1 large subunit, Activator 1 subunit 1, DNA-binding protein PO-GA, Replication factor C 140 kDa subunit, RF-C 140 kDa subunit, RFC140, Replication factor C large subunit, RFC1, RFC140
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability. [provided by RefSeq].
Background References:
- Overmeer, R.M., et al. Mol. Cell. Biol. 30(20):4828-4839(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Arora, M., et al. Leukemia 24(8):1470-1475(2010) Galbiatti, A.L., et al. Mol. Biol. Rep. (2010) In pressJugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RFC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human RFC1.
NCBI Gene ID #:
5981
NCBI Official Name:
Replication factor C subunit 1
NCBI Official Symbol:
RFC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
128 kDa
Protein Accession #:
P35251
Protein GI Number:
56757608
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P35251
User NOte:
Optimal dilutions for each application to be determined by the researcher.