EIF2S2 Antibody

ProSci
Product Code: PSI-60-960
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-960-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit beta, eIF-2-beta, EIF2S2, EIF2B
Application Note:
For WB starting dilution is: 1:1000
Background:
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.
Background References:
  • Rajesh, K., et al. Biochem. Biophys. Res. Commun. 374(2):336-340(2008)
  • Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit
Immunogen:
This EIF2S2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the C-terminal region of human EIF2S2.
NCBI Gene ID #:
8894
NCBI Official Name:
Eukaryotic translation initiation factor 2 subunit 2
NCBI Official Symbol:
EIF2S2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
P20042
Protein GI Number:
12644154
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P20042
User NOte:
Optimal dilutions for each application to be determined by the researcher.