NT5C Antibody

ProSci
Product Code: PSI-61-284
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-284-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution + U-2 OS whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution + U-2 OS whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
5'(3')-deoxyribonucleotidase, cytosolic type, 3.1.3.-, Cytosolic 5',3'-pyrimidine nucleotidase, Deoxy-5'-nucleotidase 1, dNT-1, NT5C, DNT1, UMPH2
Application Note:
For WB starting dilution is: 1:2000
Background:
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
Background References:
  • Rampazzo C.,et al.J. Biol. Chem. 275:5409-5415(2000).
  • Ota T.,et al.Nat. Genet. 36:40-45(2004).
  • Zody M.C.,et al.Nature 440:1045-1049(2006).
  • Rampazzo C.,et al.Gene 294:109-117(2002).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NT5C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from human NT5C.
NCBI Gene ID #:
30833
NCBI Official Name:
5'(3')-deoxyribonucleotidase, cytosolic type
NCBI Official Symbol:
NT5C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
Q8TCD5
Protein GI Number:
38258193
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8TCD5
User NOte:
Optimal dilutions for each application to be determined by the researcher.