DNASE1L2 Antibody

ProSci
Product Code: PSI-61-160
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-160-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution + human skeletal muscle lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution + human skeletal muscle lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Deoxyribonuclease-1-like 2, 3.1.21.-, DNase I homolog protein DHP1, Deoxyribonuclease I-like 2, DNase I-like 2, DNASE1L2, DHP1, DNAS1L2
Application Note:
For WB starting dilution is: 1:2000
Background:
Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells.
Background References:
  • Rodriguez A.M.,et al.Genomics 42:507-513(1997).
  • Shiokawa D.,et al.Genomics 84:95-105(2004).
  • Ota T.,et al.Nat. Genet. 36:40-45(2004).
  • Martin J.,et al.Nature 432:988-994(2004).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DNASE1L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 199-229 amino acids from human DNASE1L2.
NCBI Gene ID #:
1775
NCBI Official Name:
Deoxyribonuclease-1-like 2
NCBI Official Symbol:
DNASE1L2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q92874
Protein GI Number:
2494172
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q92874
User NOte:
Optimal dilutions for each application to be determined by the researcher.