SF3A2 Antibody
| Code | Size | Price |
|---|
| PSI-60-831-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Splicing factor 3A subunit 2, SF3a66, Spliceosome-associated protein 62, SAP 62, SF3A2, SAP62
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes subunit 2 of the splicing factor 3a
protein complex. The splicing factor 3a heterotrimer includes
subunits 1, 2 and 3 and is necessary for the in vitro conversion of
15S U2 snRNP into an active 17S particle that performs pre-mRNA
splicing. Subunit 2 interacts with subunit 1 through its
amino-terminus while the single zinc finger domain of subunit 2
plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also
function independently of its RNA splicing function as a
microtubule-binding protein.
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Tanackovic, G., et al. Mol. Biol. Cell 16(3):1366-1377(2005)
- Nesic, D., et al. J. Cell. Sci. 117 (PT 19), 4423-4433 (2004) :
- Takenaka, K., et al. Biochem. J. 382 (PT 1), 223-230 (2004) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This SF3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human SF3A2.
NCBI Gene ID #:
8175
NCBI Official Name:
Splicing factor 3A subunit 2
NCBI Official Symbol:
SF3A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
Q15428
Protein GI Number:
20141793
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15428
User NOte:
Optimal dilutions for each application to be determined by the researcher.