CUGBP2 Antibody

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ProSci
Product Code: PSI-59-044
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-044-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).
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Western blot analysis in Jurkat cell line lysates (35ug/lane).

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Further Information

Additional Names:
CUGBP Elav-like family member 2, CELF-2, Bruno-like protein 3, CUG triplet repeat RNA-binding protein 2, CUG-BP2, CUG-BP- and ETR-3-like factor 2, ELAV-type RNA-binding protein 3, ETR-3, Neuroblastoma apoptosis-related RNA-binding protein, hNAPOR, RNA-binding protein BRUNOL-3, CELF2, BRUNOL3, CUGBP2, ETR3, NAPOR
Application Note:
For WB starting dilution is: 1:1000
Background:
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Background References:
  • Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Xenopus, Chicken, Zebrafish, Mouse, Rat
Immunogen:
This CUGBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 481-508 amino acids from the C-terminal region of human CUGBP2.
NCBI Gene ID #:
10659
NCBI Official Name:
CUGBP Elav-like family member 2
NCBI Official Symbol:
CELF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
O95319
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O95319
User NOte:
Optimal dilutions for each application to be determined by the researcher.