RAD1 Antibody
Code | Size | Price |
---|
PSI-58-203-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
Documents
Further Information
Additional Names:
Cell cycle checkpoint protein RAD1, hRAD1, DNA repair exonuclease rad1 homolog, Rad1-like DNA damage checkpoint protein, RAD1, REC1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a component of a heterotrimeric cell
cycle checkpoint complex, known as the 9-1-1 complex, that is
activated to stop cell cycle progression in response to DNA damage
or incomplete DNA replication. The 9-1-1 complex is recruited by
RAD17 to affected sites where it may attract specialized DNA
polymerases and other DNA repair effectors. Alternatively spliced
transcript variants of this gene have been described. [provided by
RefSeq].
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Takeishi, Y., et al. Genes Cells 15(7):761-771(2010)
- Bai, H., et al. DNA Repair (Amst.) 9(5):478-487(2010)
- Park, M.J., et al. DNA Repair (Amst.) 8(10):1190-1200(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the Central region of human RAD1.
NCBI Gene ID #:
5810
NCBI Official Name:
Cell cycle checkpoint protein RAD1
NCBI Official Symbol:
RAD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
O60671
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O60671
User NOte:
Optimal dilutions for each application to be determined by the researcher.