GPLD1 Antibody
| Code | Size | Price |
|---|
| PSI-58-803-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Phosphatidylinositol-glycan-specific phospholipase D, PI-G PLD, Glycoprotein phospholipase D, Glycosyl-phosphatidylinositol-specific phospholipase D, GPI-PLD, GPI-specific phospholipase D, GPLD1, PIGPLD1
Application Note:
For WB starting dilution is: 1:1000
Background:
Many proteins are tethered to the extracellular face of
eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI)
anchor. The GPI-anchor is a glycolipid found on many blood cells.
The protein encoded by this gene is a GPI degrading enzyme.
Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes
the inositol phosphate linkage in proteins anchored by
phosphatidylinositol glycans, thereby releasing the attached
protein from the plasma membrane.
Background References:
- Speliotes, E.K., et al. Hepatology 52(3):904-912(2010)
- Tang, J.H., et al. Clin. Biochem. 42 (4-5), 400-407 (2009) :
- Yuan, X., et al. Am. J. Hum. Genet. 83(4):520-528(2008)
- Wright, M.H., et al. Biochem. Biophys. Res. Commun. 369(2):478-484(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GPLD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-306 amino acids from the Central region of human GPLD1.
NCBI Gene ID #:
2822
NCBI Official Name:
Phosphatidylinositol-glycan-specific phospholipase D
NCBI Official Symbol:
GPLD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Protein Accession #:
P80108
Protein GI Number:
126302583
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P80108
User NOte:
Optimal dilutions for each application to be determined by the researcher.