Cleavage stimulation factor 2 Antibody
| Code | Size | Price |
|---|
| PSI-60-542-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, Cleavage stimulation factor 64 kDa subunit, CSTF 64 kDa subunit, CstF-64, CSTF2
Application Note:
For WB starting dilution is: 1:1000
Background:
CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.
Background References:
- Takagaki, Y., et al., Mol. Cell 2(6):761-771 (1998).
- Martincic, K., et al., Proc. Natl. Acad. Sci. U.S.A. 95(19):11095-11100 (1998).
- Takagaki, Y., et al., Cell 87(5):941-952 (1996).
- Takagaki, Y., et al., Nature 372(6505):471-474 (1994).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This Cleavage stimulation factor 2 (CSTF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Cleavage stimulation factor 2 (CSTF2).
NCBI Gene ID #:
1478
NCBI Official Name:
Cleavage stimulation factor subunit 2
NCBI Official Symbol:
CSTF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P33240
Protein GI Number:
461847
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
P33240
User NOte:
Optimal dilutions for each application to be determined by the researcher.