MSH5 Antibody
| Code | Size | Price |
|---|
| PSI-58-814-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
MutS protein homolog 5, hMSH5, MSH5
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the mutS family of proteins
that are involved in DNA mismatch repair and meiotic recombination.
This protein is similar to a Saccharomyces cerevisiae protein that
participates in segregation fidelity and crossing-over events
during meiosis. This protein plays a role in promoting ionizing
radiation-induced apoptosis. This protein forms heterooligomers
with another member of this family, mutS homolog 4. Polymorphisms
in this gene have been linked to various human diseases, including
IgA deficiency, common variable immunodeficiency, and premature
ovarian failure. Alternative splicing results multiple transcript
variants.
Background References:
- Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
- Pozo, N.D., et al. Hum. Immunol. 71(9):861-864(2010)
- Snowden, T., et al. J. Biol. Chem. 283(1):145-154(2008)
- Sekine, H., et al. Proc. Natl. Acad. Sci. U.S.A. 104(17):7193-7198(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MSH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 525-552 amino acids from the Central region of human MSH5.
NCBI Gene ID #:
4439
NCBI Official Name:
MutS protein homolog 5
NCBI Official Symbol:
MSH5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
93 kDa
Protein Accession #:
O43196
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O43196
User NOte:
Optimal dilutions for each application to be determined by the researcher.