PRIM2 Antibody

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ProSci
Product Code: PSI-59-198
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-198-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

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Further Information

Additional Names:
DNA primase large subunit, 277-, DNA primase 58 kDa subunit, p58, PRIM2, PRIM2A
Application Note:
For WB starting dilution is: 1:1000
Background:
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the large, 58 kDa primase subunit. [provided by RefSeq].
Background References:
  • Vaithiyalingam, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13684-13689(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Weiner, B.E., et al. J. Biol. Chem. 282(46):33444-33451(2007)
  • Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This PRIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-345 amino acids from the Central region of human PRIM2.
NCBI Gene ID #:
5558
NCBI Official Name:
DNA primase large subunit
NCBI Official Symbol:
PRIM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
P49643
Protein GI Number:
51338777
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P49643
User NOte:
Optimal dilutions for each application to be determined by the researcher.