NUDT2 Antibody
| Code | Size | Price |
|---|
| PSI-58-275-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2, NUDT2, APAH1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the MutT family of
nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase
family. The gene product possesses a modification of the MutT
sequence motif found in certain nucleotide pyrophosphatases. The
enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is
responsible for maintaining the intracellular level of the
dinucleotide Ap4A, the function of which has yet to be established.
This gene may be a candidate tumor suppressor gene. Alternative
splicing has been observed at this locus and three transcript
variants, all encoding the same protein, have been identified.
Background References:
- Vasilenko, N., et al. Virol. J. 7, 31 (2010) :
- Swarbrick, J.D., et al. J. Biol. Chem. 280(9):8471-8481(2005)
- Swarbrick, J.D., et al. J. Biomol. NMR 31(2):181-182(2005)
- Pitcher, W.H. III, et al. Antiviral Res. 58(3):227-233(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NUDT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the Central region of human NUDT2.
NCBI Gene ID #:
318
NCBI Official Name:
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
NCBI Official Symbol:
NUDT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
P50583
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P50583
User NOte:
Optimal dilutions for each application to be determined by the researcher.