PARG Antibody

ProSci
Product Code: PSI-58-669
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-669-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Further Information

Additional Names:
Poly(ADP-ribose) glycohydrolase, PARG
Application Note:
For WB starting dilution is: 1:1000
Background:
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products.
Background References:
  • Whatcott, C.J., et al. Exp. Cell Res. 315(20):3477-3485(2009)
  • Frizzell, K.M., et al. J. Biol. Chem. 284(49):33926-33938(2009)
  • Erdelyi, K., et al. FASEB J. 23(10):3553-3563(2009)
  • Ame, J.C., et al. J. Cell. Sci. 122 (PT 12), 1990-2002 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PARG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-849 amino acids from the C-terminal region of human PARG.
NCBI Gene ID #:
8505
NCBI Official Name:
Poly(ADP-ribose) glycohydrolase
NCBI Official Symbol:
PARG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
111 kDa
Protein Accession #:
Q86W56
Protein GI Number:
56417893
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q86W56
User NOte:
Optimal dilutions for each application to be determined by the researcher.