TRIM37 Antibody
Code | Size | Price |
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PSI-56-970-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
E3 ubiquitin-protein ligase TRIM37, 632-, Mulibrey nanism protein, Tripartite motif-containing protein 37, TRIM37, KIAA0898, MUL, POB1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the tripartite motif (TRIM)
family, whose members are involved in diverse cellular functions
such as developmental patterning and oncogenesis. The TRIM motif
includes zinc-binding domains, a RING finger region, a B-box motif
and a coiled-coil domain. The RING finger and B-box domains chelate
zinc and might be involved in protein-protein and/or
protein-nucleic acid interactions. The gene mutations are
associated with mulibrey (muscle-liver-brain-eye) nanism, an
autosomal recessive disorder that involves several tissues of
mesodermal origin. Alternatively spliced transcript variants
encoding the same protein have been identified. [provided by
RefSeq].
Background References:
- Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
- Karlberg, S., et al. Mod. Pathol. 22(4):570-578(2009)
- Doganc, T., et al. Clin. Dysmorphol. 16(3):173-176(2007)
- Hamalainen, R.H., et al. Clin. Genet. 70(6):473-479(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRIM37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 936-964 amino acids from the C-terminal region of human TRIM37.
NCBI Gene ID #:
4591
NCBI Official Name:
E3 ubiquitin-protein ligase TRIM37
NCBI Official Symbol:
TRIM37
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
108 kDa
Protein Accession #:
O94972
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O94972
User NOte:
Optimal dilutions for each application to be determined by the researcher.