ST6GALNAC4 Antibody
| Code | Size | Price |
|---|
| PSI-60-240-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase, NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase, ST6GalNAc IV, ST6GalNAcIV, Sialyltransferase 3C, SIAT3-C, Sialyltransferase 7D, SIAT7-D, ST6GALNAC4, SIAT3C, SIAT7D
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a type II membrane
protein that catalyzes the transfer of sialic acid from CMP-sialic
acid to galactose-containing substrates. The encoded protein
prefers glycoproteins rather than glycolipids as substrates and
shows restricted substrate specificity, utilizing only the
trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In
addition, it is involved in the synthesis of ganglioside GD1A from
GM1B. The encoded protein is normally found in the Golgi apparatus
but can be proteolytically processed to a soluble form. This
protein is a member of glycosyltransferase family 29. Transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Yoshino, H., et al. Brain Res. 1227, 216-220 (2008) :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ST6GALNAC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human ST6GALNAC4.
NCBI Gene ID #:
27090
NCBI Official Name:
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase
NCBI Official Symbol:
ST6GALNAC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q9H4F1
Protein GI Number:
21759443
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H4F1
User NOte:
Optimal dilutions for each application to be determined by the researcher.