REXO2 Antibody

ProSci
Product Code: PSI-59-066
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-066-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Oligoribonuclease, mitochondrial, 31--, RNA exonuclease 2 homolog, Small fragment nuclease, REXO2, SFN, SMFN
Application Note:
For WB starting dilution is: 1:1000
Background:
Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mononucleotides in a sequential manner.
Background References:
  • Young Park, A., et al. Protein Expr. Purif. 57(2):180-187(2008)
  • Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
  • Ito, S., et al. Photochem. Photobiol. 80(2):281-285(2004)
  • Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This REXO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-157 amino acids from the Central region of human REXO2.
NCBI Gene ID #:
25996
NCBI Official Name:
Oligoribonuclease, mitochondrial
NCBI Official Symbol:
REXO2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
Q9Y3B8
Protein GI Number:
116242694
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9Y3B8
User NOte:
Optimal dilutions for each application to be determined by the researcher.