TTDN1 Antibody

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ProSci
Product Code: PSI-59-300
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-300-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

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Further Information

Additional Names:
M-phase-specific PLK1-interacting protein, TTD non-photosensitive 1 protein, MPLKIP, C7orf11, TTDN1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.
Background References:
  • Zhang, Y., et al. Cell. Mol. Life Sci. 64(5):632-640(2007)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Botta, E., et al. Hum. Mutat. 28(1):92-96(2007)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This TTDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the C-terminal region of human TTDN1.
NCBI Gene ID #:
136647
NCBI Official Name:
M-phase-specific PLK1-interacting protein
NCBI Official Symbol:
MPLKIP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
Q8TAP9
Protein GI Number:
71153365
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8TAP9
User NOte:
Optimal dilutions for each application to be determined by the researcher.