MRPS15 Antibody
| Code | Size | Price |
|---|
| PSI-58-526-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
28S ribosomal protein S15, mitochondrial, MRP-S15, S15mt, MRPS15, RPMS15
Application Note:
For WB starting dilution is: 1:1000
Background:
Mammalian mitochondrial ribosomal proteins are encoded by
nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a
small 28S subunit and a large 39S subunit. They have an estimated
75% protein to rRNA composition compared to prokaryotic ribosomes,
where this ratio is reversed. Another difference between mammalian
mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the
mitoribosome differ greatly in sequence, and sometimes in
biochemical properties, which prevents easy recognition by sequence
homology. This gene encodes a 28S subunit protein that belongs to
the ribosomal protein S15P family. The encoded protein is more than
two times the size of its E. coli counterpart, with the 12S rRNA
binding sites conserved. Between human and mouse, the encoded
protein is the least conserved among small subunit ribosomal
proteins. Pseudogenes corresponding to this gene are found on
chromosomes 15q and 19q.
Background References:
- Zhang, Z., et al. Genomics 81(5):468-480(2003)
- Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :
- Suzuki, T., et al. J. Biol. Chem. 276(35):33181-33195(2001)
- Cavdar Koc, E., et al. J. Biol. Chem. 276(22):19363-19374(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MRPS15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-153 amino acids from the Central region of human MRPS15.
NCBI Gene ID #:
64960
NCBI Official Name:
28S ribosomal protein S15, mitochondrial
NCBI Official Symbol:
MRPS15
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
P82914
Protein GI Number:
13633907
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P82914
User NOte:
Optimal dilutions for each application to be determined by the researcher.