RPS19 Antibody
Code | Size | Price |
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PSI-56-194-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
40S ribosomal protein S19, RPS19
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
Ribosomes, the organelles that catalyze protein synthesis,
consist of a small 40S subunit and a large 60S subunit. Together
these subunits are composed of 4 RNA species and approximately 80
structurally distinct proteins. This gene encodes a ribosomal
protein that is a component of the 40S subunit. The protein belongs
to the S19E family of ribosomal proteins. It is located in the
cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia
(DBA), a constitutional erythroblastopenia characterized by absent
or decreased erythroid precursors, in a subset of patients. This
suggests a possible extra-ribosomal function for this gene in
erythropoietic differentiation and proliferation, in addition to
its ribosomal function. Higher expression levels of this gene in
some primary colon carcinomas compared to matched normal colon
tissues has been observed. As is typical for genes encoding
ribosomal proteins, there are multiple processed pseudogenes of
this gene dispersed through the genome.
Background References:
- Devlin, E.E., et al. Blood 116(15):2826-2835(2010)
- Iadevaia, V., et al. Oncogene 29(40):5490-5499(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Nishiura, H., et al. Apoptosis 15(8):966-981(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This RPS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human RPS19.
NCBI Gene ID #:
6223
NCBI Official Name:
40S ribosomal protein S19
NCBI Official Symbol:
RPS19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
P39019
Protein GI Number:
730640
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P39019
User NOte:
Optimal dilutions for each application to be determined by the researcher.