SELPLG Antibody
| Code | Size | Price |
|---|
| PSI-55-196-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
SELPLG is the high affinity counter-receptor for
P-selectin on myeloid cells and stimulated T lymphocytes. As such,
it plays a critical role in the tethering of these cells to
activated platelets or endothelia expressing P-selectin. The
organization of the SELPG gene closely resembles that of CD43 and
the human platelet glycoprotein GpIb-alpha both of which have an
intron in the 5-prime-noncoding region, a long second exon
containing the complete coding region, and TATA-less promoters.
Background References:
- Elmas, E., et al. J. Cardiovasc. Electrophysiol. 21(11):1260-1265(2010)
- Luan, S.L., et al. J. Pathol. 222(2):166-179(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Russo, H.M., et al. Circ. Res. 107(3):388-397(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SELPLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-405 amino acids from the C-terminal region of human SELPLG.
NCBI Gene ID #:
6404
NCBI Official Name:
P-selectin glycoprotein ligand 1
NCBI Official Symbol:
SELPLG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q14242
Protein GI Number:
2498904
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q14242
User NOte:
Optimal dilutions for each application to be determined by the researcher.