ALX4 Antibody
| Code | Size | Price |
|---|
| PSI-55-158-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Homeobox protein aristaless-like 4, ALX4, KIAA1788
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a paired-like homeodomain transcription
factor expressed in the mesenchyme of developing bones, limbs,
hair, teeth, and mammary tissue. Mutations in this gene cause
parietal foramina 2 (PFM2); an autosomal dominant disease
characterized by deficient ossification of the parietal bones.
Mutations in this gene also cause a form of frontonasal dysplasia
with alopecia and hypogonadism; suggesting a role for this gene in
craniofacial development, mesenchymal-epithelial communication, and
hair follicle development. Deletion of a segment of chromosome 11
containing this gene, del(11)(p11p12), causes Potocki-Shaffer
syndrome (PSS); a syndrome characterized by craniofacial anomalies,
mental retardation, multiple exostoses, and genital abnormalities
in males. In mouse, this gene has been shown to use dual
translation initiation sites located 16 codons apart. [provided by
RefSeq].
Background References:
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Tanzer, M., et al. PLoS ONE(2), E9061 (2010) :
- Kayserili, H., et al. Hum. Mol. Genet. 18(22):4357-4366(2009)
- Chang, H., et al. J. Clin. Pathol. 62(10):908-914(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This ALX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-275 amino acids from the Central region of human ALX4.
NCBI Gene ID #:
60529
NCBI Official Name:
Homeobox protein aristaless-like 4
NCBI Official Symbol:
ALX4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q9H161
Protein GI Number:
254763249
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H161
User NOte:
Optimal dilutions for each application to be determined by the researcher.