HIST3H3 Antibody
| Code | Size | Price |
|---|
| PSI-56-287-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone H31t, H3/t, H3t, H3/g, HIST3H3, H3FT
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA
wrapped around a histone octamer composed of pairs of each of the
four core histones (H2A, H2B, H3, and H4). The chromatin fiber is
further compacted through the interaction of a linker histone, H1,
with the DNA between the nucleosomes to form higher order chromatin
structures. This gene is intronless and encodes a member of the
histone H3 family. Transcripts from this gene lack polyA tails;
instead, they contain a palindromic termination element. This gene
is located separately from the other H3 genes that are in the
histone gene cluster on chromosome 6p22-p21.3. [provided by
RefSeq].
Background References:
- Tachiwana, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(23):10454-10459(2010)
- Nair, S.S., et al. EMBO Rep. 11(6):438-444(2010)
- Rampakakis, E., et al. J. Cell. Biochem. 108(2):400-407(2009)
- Mochizuki, K., et al. Biochem. Biophys. Res. Commun. 371(2):324-327(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HIST3H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the Central region of human HIST3H3.
NCBI Gene ID #:
8290
NCBI Official Name:
Histone H3.1t
NCBI Official Symbol:
HIST3H3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
Q16695
Protein GI Number:
18202512
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q16695
User NOte:
Optimal dilutions for each application to be determined by the researcher.