HOXC6 Antibody

ProSci
Product Code: PSI-61-847
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-847-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in PC-3 cell line lysates (35ug/lane).
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Flow cytometric analysis of U251 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot analysis in PC-3 cell line lysates (35ug/lane).
Flow cytometric analysis of U251 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Further Information

Additional Names:
Homeobox protein Hox-C6, Homeobox protein CP25, Homeobox protein HHOC8, Homeobox protein Hox-3C, HOXC6, HOX3C
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
This protein belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon.
Background References:
  • Zhang, X., et al. J. Cell. Mol. Med. 11(2):299-306(2007)
  • Hori, Y., et al. PLoS Med.(4), E103 (2005)
  • Ramachandran, S., et al. Oncogene 24(1):188-198(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This HOXC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-227 amino acids from the C-terminal region of human HOXC6.
NCBI Gene ID #:
3223
NCBI Official Name:
Homeobox protein Hox-C6
NCBI Official Symbol:
HOXC6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
P09630
Protein GI Number:
115502398
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P09630
User NOte:
Optimal dilutions for each application to be determined by the researcher.