TADA3L Antibody
| Code | Size | Price |
|---|
| PSI-57-974-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcriptional adapter 3, ADA3 homolog, hADA3, STAF54, Transcriptional adapter 3-like, ADA3-like protein, TADA3, ADA3, TADA3L
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
Many DNA-binding transcriptional activator proteins
enhance the initiation rate of RNA polymerase II-mediated gene
transcription by interacting functionally with the general
transcription machinery bound at the basal promoter. Adaptor
proteins are usually required for this activation, possibly to
acetylate and destabilize nucleosomes, thereby relieving chromatin
constraints at the promoter. The protein encoded by this gene is a
transcriptional activator adaptor and has been found to be part of
the PCAF histone acetylase complex. In addition, it associates with
the tumor suppressor protein p53 and is required for full activity
of p53 and p53-mediated apoptosis. At least four alternatively
spliced variants have been found for this gene, but the full-length
nature of some variants has not been determined. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Li, C.W., et al. Nucleic Acids Res. 38(16):5291-5303(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Hu, Y., et al. Cancer Invest. 27(3):298-306(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Xenopus, Bovine, Zebrafish, Mouse, Rat
Immunogen:
This TADA3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-414 amino acids from the C-terminal region of human TADA3L.
NCBI Gene ID #:
10474
NCBI Official Name:
Transcriptional adapter 3
NCBI Official Symbol:
TADA3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
O75528
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O75528
User NOte:
Optimal dilutions for each application to be determined by the researcher.