FANCG Antibody

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ProSci
Product Code: PSI-57-913
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-913-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
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FANCG Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
FANCG Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Documents

Further Information

Additional Names:
Fanconi anemia group G protein, Protein FACG, DNA repair protein XRCC9, FANCG, XRCC9
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Wang, C., et al. Biochemistry 49(26):5560-5569(2010)
  • Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
  • Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FANCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-568 amino acids from the C-terminal region of human FANCG.
NCBI Gene ID #:
2189
NCBI Official Name:
Fanconi anemia group G protein
NCBI Official Symbol:
FANCG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
O15287
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O15287
User NOte:
Optimal dilutions for each application to be determined by the researcher.