NR1D2 Antibody

ProSci
Product Code: PSI-58-042
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-042-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).
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NR1D2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in Hela cell line lysates (35ug/lane).
NR1D2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Nuclear receptor subfamily 1 group D member 2, Orphan nuclear hormone receptor BD73, Rev-erb alpha-related receptor, RVR, Rev-erb-beta, V-erbA-related protein 1-related, EAR-1R, NR1D2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
Background References:
  • Campos-de-Sousa, S., et al. J. Biol. Rhythms 25(2):132-137(2010)
  • Burris, T.P. Mol. Endocrinol. 22(7):1509-1520(2008)
  • Liu, A.C., et al. PLoS Genet.(2), E1000023 (2008) :
  • Wang, J., et al. Biochim. Biophys. Acta 1783(2):224-236(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NR1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-294 amino acids from the Central region of human NR1D2.
NCBI Gene ID #:
9975
NCBI Official Name:
Nuclear receptor subfamily 1 group D member 2
NCBI Official Symbol:
NR1D2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
Q14995
Protein GI Number:
215274122
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q14995
User NOte:
Optimal dilutions for each application to be determined by the researcher.