EIF4B Antibody
Code | Size | Price |
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PSI-60-583-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Eukaryotic translation initiation factor 4B, eIF-4B, EIF4B
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
EIF4B is required for the binding of mRNA to ribosomes. It functions in close association with EIF4-F and EIF4-A by binding near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. This gene also promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F
Background References:
- Doepker, R.C., et al., J. Virol. 78(9):4684-4699 (2004).
- Fleming, K., et al., Biochemistry 42(30):8966-8975 (2003).
- Milburn, S.C., et al., EMBO J. 9(9):2783-2790 (1990).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This EIF4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 546-575 amino acids from the C-terminal region of human EIF4B.
NCBI Gene ID #:
1975
NCBI Official Name:
Eukaryotic translation initiation factor 4B
NCBI Official Symbol:
EIF4B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
P23588
Protein GI Number:
205371761
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
P23588
User NOte:
Optimal dilutions for each application to be determined by the researcher.