EIF4H Antibody

ProSci
Product Code: PSI-56-537
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-537-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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EIF4H Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in MDA-MB231,Hela cell line lysates (35ug/lane).

EIF4H Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in MDA-MB231,Hela cell line lysates (35ug/lane).

Further Information

Additional Names:
Eukaryotic translation initiation factor 4H, eIF-4H, Williams-Beuren syndrome chromosomal region 1 protein, EIF4H, KIAA0038, WBSCR1, WSCR1
Application Note:
For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000
Background:
This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
Background References:
  • Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
  • Zhu, X., et al. Genet. Epidemiol. 34(2):171-187(2010)
  • Mokas, S., et al. Mol. Biol. Cell 20(11):2673-2683(2009)
  • Marintchev, A., et al. Cell 136(3):447-460(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This EIF4H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the Central region of human EIF4H.
NCBI Gene ID #:
7458
NCBI Official Name:
Eukaryotic translation initiation factor 4H
NCBI Official Symbol:
EIF4H
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
Q15056
Protein GI Number:
18276665
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15056
User NOte:
Optimal dilutions for each application to be determined by the researcher.