TARBP2 Antibody
| Code | Size | Price |
|---|
| PSI-57-481-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TRBP
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
HIV-1, the causative agent of acquired immunodeficiency
syndrome (AIDS), contains an RNA genome that produces a
chromosomally integrated DNA during the replicative cycle.
Activation of HIV-1 gene expression by the transactivator Tat is
dependent on an RNA regulatory element (TAR) located downstream of
the transcription initiation site. The protein encoded by this gene
binds between the bulge and the loop of the HIV-1 TAR RNA
regulatory element and activates HIV-1 gene expression in synergy
with the viral Tat protein. Alternative splicing results in
multiple transcript variants encoding different isoforms. This gene
also has a pseudogene.
Background References:
- Garre, P., et al. Nat. Genet. 42(10):817-818(2010)
- Wilker, E.H., et al. Environ. Health Perspect. 118(7):943-948(2010)
- Boni, V., et al. Pharmacogenomics J. (2010) In press :
- Wang, H.W., et al. Nat. Struct. Mol. Biol. 16(11):1148-1153(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat, Xenopus
Immunogen:
This TARBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human TARBP2.
NCBI Gene ID #:
6895
NCBI Official Name:
RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}
NCBI Official Symbol:
TARBP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q15633
Protein GI Number:
209572714
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15633
User NOte:
Optimal dilutions for each application to be determined by the researcher.