DPYS Antibody
| Code | Size | Price |
|---|
| PSI-57-041-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dihydropyrimidinase, DHP, DHPase, Dihydropyrimidine amidohydrolase, Hydantoinase, DPYS
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Dihydropyrimidinase catalyzes the conversion of
5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism.
Dihydropyrimidinase is expressed at a high level in liver and
kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript.
Defects in the DPYS gene are linked to dihydropyrimidinuria.
Background References:
- Kim, H.Y., et al. BMB Rep 43(8):547-553(2010)
- van Kuilenburg, A.B., et al. Biochim. Biophys. Acta 1802 (7-8), 639-648 (2010) :
- Fidlerova, J., et al. Cancer Chemother. Pharmacol. 65(4):661-669(2010)
- Thomas, H.R., et al. Pharmacogenet. Genomics 18(1):25-35(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DPYS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human DPYS.
NCBI Gene ID #:
1807
NCBI Official Name:
Dihydropyrimidinase
NCBI Official Symbol:
DPYS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q14117
Protein GI Number:
3122049
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q14117
User NOte:
Optimal dilutions for each application to be determined by the researcher.