HIST1H1D Antibody
| Code | Size | Price |
|---|
| PSI-57-240-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone H13, Histone H1c, Histone H1s-2, HIST1H1D, H1F3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Histones are basic nuclear proteins responsible for
nucleosome structure of the chromosomal fiber in eukaryotes. Two
molecules of each of the four core histones (H2A, H2B, H3, and H4)
form an octamer, around which approximately 146 bp of DNA is
wrapped in repeating units, called nucleosomes. The linker histone,
H1, interacts with linker DNA between nucleosomes and functions in
the compaction of chromatin into higher order structures. This gene
is intronless and encodes a member of the histone H1 family.
Transcripts from this gene lack polyA tails but instead contain a
palindromic termination element. This gene is found in the large
histone gene cluster on chromosome 6.
Background References:
- Kim, J.J., et al. J. Hum. Genet. 55(1):27-31(2010)
- Soranzo, N., et al. PLoS Genet.(4), E1000445 (2009) :
- Sovio, U., et al. PLoS Genet.(3), E1000409 (2009) :
- Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HIST1H1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human HIST1H1D.
NCBI Gene ID #:
3007
NCBI Official Name:
Histone H1.3
NCBI Official Symbol:
HIST1H1D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
P16402
Protein GI Number:
121925
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P16402
User NOte:
Optimal dilutions for each application to be determined by the researcher.