ZRSR2 Antibody

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ProSci
Product Code: PSI-60-983
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-983-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Immunohistochemical analysis of paraffin-embedded H. prostate section using ZRSR2 Antibody . Antibody was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
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Western blot analysis in 293,HepG2,HL-60,Jurkat,MCF-7,ZR-75-1 cell line lysates (35ug/lane).
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Immunohistochemical analysis of paraffin-embedded H. prostate section using ZRSR2 Antibody . Antibody was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Western blot analysis in 293,HepG2,HL-60,Jurkat,MCF-7,ZR-75-1 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2, CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2, Renal carcinoma antigen NY-REN-20, U2(RNU2) small nuclear RNA auxiliary factor 1-like 2, U2AF35-related protein, URP, ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2, URP
Application Note:
For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:1000
Background:
Pre-mRNA-binding protein required for splicing of both U2-and U12-type introns. Selectively interacts with the 3'-splice site of U2-and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.
Background References:
  • Kitagawa K., et al. Genomics 30:257-263(1995).
  • Ross M.T., et al. Nature 434:325-337(2005).
  • Tronchere H., et al. Nature 388:397-400(1997).
  • Scanlan M.J., et al. Int. J. Cancer 83:456-464(1999).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ZRSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human ZRSR2.
NCBI Gene ID #:
8233
NCBI Official Name:
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
NCBI Official Symbol:
ZRSR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q15696
Protein GI Number:
2833266
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15696
User NOte:
Optimal dilutions for each application to be determined by the researcher.