HNRNPC Antibody
| Code | Size | Price |
|---|
| PSI-55-373-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC
Application Note:
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
For WB starting dilution is: 1:1000
Background:
This gene belongs to the subfamily of ubiquitously
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are RNA binding proteins and they complex with heterogeneous
nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs
in the nucleus and appear to influence pre-mRNA processing and
other aspects of mRNA metabolism and transport. While all of the
hnRNPs are present in the nucleus, some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic
acid binding properties. The protein encoded by this gene can act
as a tetramer and is involved in the assembly of 40S hnRNP
particles. Multiple transcript variants encoding at least two
different isoforms have been described for this gene. [provided by
RefSeq].
Background References:
- Konig, J., et al. Nat. Struct. Mol. Biol. 17(7):909-915(2010)
- Lee, E.K., et al. Nat. Struct. Mol. Biol. 17(6):732-739(2010)
- Brunner, J.E., et al. Virology 400(2):240-247(2010)
- Ertel, K.J., et al. J. Virol. 84(9):4229-4242(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit
Immunogen:
This HNRNPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.
NCBI Gene ID #:
3183
NCBI Official Name:
Heterogeneous nuclear ribonucleoproteins C1/C2
NCBI Official Symbol:
HNRNPC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
P07910
Protein GI Number:
108935845
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P07910
User NOte:
Optimal dilutions for each application to be determined by the researcher.