HNRNPM Antibody
| Code | Size | Price |
|---|
| PSI-57-415-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Heterogeneous nuclear ribonucleoprotein M, hnRNP M, HNRNPM, HNRPM, NAGR1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene belongs to the subfamily of ubiquitously
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are RNA binding proteins and they complex with heterogeneous
nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs
in the nucleus and appear to influence pre-mRNA processing and
other aspects of mRNA metabolism and transport. While all of the
hnRNPs are present in the nucleus, some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic
acid binding properties. The protein encoded by this gene has three
repeats of quasi-RRM domains that bind to RNAs. This protein also
constitutes a monomer of the N-acetylglucosamine-specific receptor
which is postulated to trigger selective recycling of immature
GlcNAc-bearing thyroglobulin molecules. Multiple alternatively
spliced transcript variants are known for this gene but only two
transcripts has been isolated.
Background References:
- Lleres, D., et al. EMBO Rep. 11(6):445-451(2010)
- Marko, M., et al. Exp. Cell Res. 316(3):390-400(2010)
- Russo, A., et al. Biochim. Biophys. Acta 1779(12):820-829(2008)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HNRNPM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HNRNPM.
NCBI Gene ID #:
4670
NCBI Official Name:
Heterogeneous nuclear ribonucleoprotein M
NCBI Official Symbol:
HNRNPM
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
78 kDa
Protein Accession #:
P52272
Protein GI Number:
55977747
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P52272
User NOte:
Optimal dilutions for each application to be determined by the researcher.