NONO Antibody
Code | Size | Price |
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PSI-57-268-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Non-POU domain-containing octamer-binding protein, NonO protein, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, DNA-binding p52/p100 complex, 52 kDa subunit, NMT55, p54(nrb), p54nrb, NONO, NRB54
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes an RNA-binding protein which plays
various roles in the nucleus, including transcriptional regulation
and RNA splicing. A rearrangement between this gene and the
transcription factor E3 gene has been observed in papillary renal
cell carcinoma. Alternatively spliced transcript variants have been
described. Pseudogenes exist on Chromosomes 2 and 16. [provided by
RefSeq].
Background References:
- Marko, M., et al. Exp. Cell Res. 316(3):390-400(2010)
- Dong, X., et al. Mol. Endocrinol. 23(8):1147-1160(2009)
- Sikora, D., et al. Virology 390(1):71-78(2009)
- Clemson, C.M., et al. Mol. Cell 33(6):717-726(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This NONO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human NONO.
NCBI Gene ID #:
4841
NCBI Official Name:
Non-POU domain-containing octamer-binding protein
NCBI Official Symbol:
NONO
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
Q15233
Protein GI Number:
67469924
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15233
User NOte:
Optimal dilutions for each application to be determined by the researcher.