POLR2J Antibody
| Code | Size | Price |
|---|
| PSI-57-598-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
DNA-directed RNA polymerase II subunit RPB11-a, RNA polymerase II subunit B11-a, RPB11a, DNA-directed RNA polymerase II subunit J-1, RNA polymerase II 133 kDa subunit, POLR2J, POLR2J1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a subunit of RNA polymerase II, the
polymerase responsible for synthesizing messenger RNA in
eukaryotes. The product of this gene exists as a heterodimer with
another polymerase subunit; together they form a core subassembly
unit of the polymerase. Two similar genes are located nearby on
chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.
Background References:
- Michiels, S., et al. Carcinogenesis 30(5):763-768(2009)
- Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
- Shpakovskii, D.G., et al. Bioorg. Khim. 30(6):621-625(2004)
- Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 100(22):12666-12671(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This POLR2J antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the C-terminal region of human POLR2J.
NCBI Gene ID #:
5439
NCBI Official Name:
DNA-directed RNA polymerase II subunit RPB11-a
NCBI Official Symbol:
POLR2J
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
13 kDa
Protein Accession #:
P52435
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P52435
User NOte:
Optimal dilutions for each application to be determined by the researcher.