SLC9A2 Antibody

ProSci
Product Code: PSI-56-594
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-594-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
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SLC9A2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
SLC9A2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Sodium/hydrogen exchanger 2, Na(+)/H(+) exchanger 2, NHE-2, Solute carrier family 9 member 2, SLC9A2, NHE2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
SLC9A2 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Son, E.J., et al. J. Cell. Biochem. 107(5):965-972(2009)
  • Joly, F., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (1), G116-G123 (2009) :
  • Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 296 (2), G202-G210 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLC9A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-783 amino acids from the C-terminal region of human SLC9A2.
NCBI Gene ID #:
6549
NCBI Official Name:
Sodium/hydrogen exchanger 2
NCBI Official Symbol:
SLC9A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Protein Accession #:
Q9UBY0
Protein GI Number:
19924293
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9UBY0
User NOte:
Optimal dilutions for each application to be determined by the researcher.