NPHP3 Antibody
| Code | Size | Price |
|---|
| PSI-56-625-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nephrocystin-3, NPHP3, KIAA2000
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a protein containing a coiled-coil (CC)
domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico
peptide repeat (TPR) domain. The encoded protein interacts with
nephrocystin and may function in renal tubular development and
function. Mutations in this gene are associated with
nephronophthisis type 3. Multiple splice variants have been
described but their full-length nature has not been determined.
Background References:
- Simpson, M.A., et al. Am. J. Kidney Dis. 53(5):790-795(2009)
- Tory, K., et al. Kidney Int. 75(8):839-847(2009)
- Bergmann, C., et al. Am. J. Hum. Genet. 82(4):959-970(2008)
- Hoefele, J., et al. J. Am. Soc. Nephrol. 18(10):2789-2795(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Xenopus
Immunogen:
This NPHP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human NPHP3.
NCBI Gene ID #:
27031
NCBI Official Name:
Nephrocystin-3
NCBI Official Symbol:
NPHP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
151 kDa
Protein Accession #:
Q7Z494
Protein GI Number:
68565783
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q7Z494
User NOte:
Optimal dilutions for each application to be determined by the researcher.