PAEP Antibody
| Code | Size | Price |
|---|
| PSI-57-832-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Glycodelin, GD, Placental protein 14, PP14, Pregnancy-associated endometrial alpha-2 globulin, PAEG, PEG, Progestagen-associated endometrial protein, Progesterone-associated endometrial protein, PAEP
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene is a member of the kernel lipocalin superfamily
whose members share relatively low sequence similarity but have
highly conserved exon/intron structure and three-dimensional
protein folding. Most lipocalins are clustered on the long arm of
chromosome 9. The encoded glycoprotein has been previously referred
to as pregnancy-associated endometrial alpha-2-globulin, placental
protein 14, and glycodelin, but has been officially named
progestagen-associated endometrial protein. Three distinct forms,
with identical protein backbones but different glycosylation
profiles, are found in amniotic fluid, follicular fluid and seminal
plasma of the reproductive system. These glycoproteins have
distinct and essential roles in regulating a uterine environment
suitable for pregnancy and in the timing and occurrence of the
appropriate sequence of events in the fertilization process. A
number of alternatively spliced transcript variants have been
observed at this locus, but the full-length nature of only two,
each encoding the same protein, has been determined. [provided by
RefSeq].
Background References:
- Soni, C., et al. Mol. Immunol. 47(15):2458-2466(2010)
- Lee, C.L., et al. Fertil. Steril. 94(2):769-771(2010)
- Tsviliana, A., et al. Anticancer Res. 30(5):1637-1640(2010)
- Scholz, C., et al. Anticancer Res. 30(5):1599-1603(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PAEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of human PAEP.
NCBI Gene ID #:
5047
NCBI Official Name:
Glycodelin
NCBI Official Symbol:
PAEP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
P09466
Protein GI Number:
130701
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P09466
User NOte:
Optimal dilutions for each application to be determined by the researcher.