SPRR1B Antibody
| Code | Size | Price |
|---|
| PSI-63-762-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cornifin-B, 149 kDa pancornulin, Small proline-rich protein IB, SPR-IB, SPRR1B
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
SPRR1B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Background References:
- Stemmler,S., et.al., Int. J. Immunogenet. 36 (4), 217-222 (2009)
- Kainu,K., et.al., Exp. Dermatol. 18 (2), 109-115 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-89 amino acids from the C-terminal region of human SPRR1B.
NCBI Gene ID #:
6699
NCBI Official Name:
Cornifin-B
NCBI Official Symbol:
SPRR1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
10 kDa
Protein Accession #:
P22528
Protein GI Number:
84028265
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P22528
User NOte:
Optimal dilutions for each application to be determined by the researcher.