CPSF3L Antibody
| Code | Size | Price |
|---|
| PSI-55-677-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Integrator complex subunit 11, Int11, 3127-, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, RC-68, CPSF3L, INTS11, RC68
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
The Integrator complex contains at least 12 subunits and
associates with the C-terminal domain of RNA polymerase II large
subunit (POLR2A; MIM 180660) and mediates the 3-prime end
processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2
(RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of
the Integrator complex (Baillat et al., 2005 [PubMed
16239144]).
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Baillat, D., et al. Cell 123(2):265-276(2005)
- Dominski, Z., et al. Mol. Cell. Biol. 25(4):1489-1500(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human CPSF3L.
NCBI Gene ID #:
54973
NCBI Official Name:
Integrator complex subunit 11
NCBI Official Symbol:
CPSF3L
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q5TA45
Protein GI Number:
118572557
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q5TA45
User NOte:
Optimal dilutions for each application to be determined by the researcher.