D SUMO Antibody
| Code | Size | Price |
|---|
| PSI-56-712-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Drosophila (fruit fly)
- Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
CG4494-PA; LD07775p; Smt3; Ubiquitin-like protein SMT3
Application Note:
For WB starting dilution is: 1:1000
Background:
Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.
Background References:
- Muller S, et al., Nat Rev Mol Cell Biol. 2001 2(3):202-10 Review.
- Hochstrasser M. Cell. 2001 107(1):5-8. Review.
- Kahyo T, et al., Mol Cell. 2001 Sep;8(3):713-8.
- Yeh ET, et al., Gene. 2000 May 2;248(1-2):1-14. Review.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the C-terminal region of human Drosophila SUMO.
NCBI Gene ID #:
33981
NCBI Official Name:
CG4494-PA
NCBI Official Symbol:
O97102
NCBI Organism:
Drosophila melanogaster
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
10 kDa
Protein Accession #:
O97102
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
O97102
User NOte:
Optimal dilutions for each application to be determined by the researcher.