ASAP3 Antibody

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ProSci
Product Code: PSI-55-552
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-552-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Hamster
  • Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
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Western blot analysis in CHO cell line lysates (35ug/lane).
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Western blot analysis in CHO cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, Development and differentiation-enhancing factor-like 1, Protein up-regulated in liver cancer 1, ASAP3, DDEFL1, UPLC1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants.
Background References:
  • Ismail, S.A., et al. Cell 141(5):812-821(2010)
  • Ha, V.L., et al. J. Biol. Chem. 283(22):14915-14926(2008)
  • Fang, Z., et al. Mol. Cell Proteomics 5(8):1437-1449(2006)
  • Okabe, H., et al. Int. J. Oncol. 24(1):43-48(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ASAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human ASAP3.
NCBI Gene ID #:
55616
NCBI Official Name:
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
NCBI Official Symbol:
ASAP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
99 kDa
Protein Accession #:
Q8TDY4
Protein GI Number:
74751433
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q8TDY4
User NOte:
Optimal dilutions for each application to be determined by the researcher.