ENTPD8 Antibody

ProSci
Product Code: PSI-61-813
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-813-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Hamster
  • Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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(LEFT)Western blot analysis of ENTPD8 Antibody in K562 cell line lysates (35ug/lane).ENTPD8 (arrow) was detected using the purified Pab. (RIGHT)Western blot analysis of ENTPD8 Antibody in CHO cell line lysates (35ug/lane).ENTPD8 (arrow) was detected using the purified Pab.

(LEFT)Western blot analysis of ENTPD8 Antibody in K562 cell line lysates (35ug/lane).ENTPD8 (arrow) was detected using the purified Pab. (RIGHT)Western blot analysis of ENTPD8 Antibody in CHO cell line lysates (35ug/lane).ENTPD8 (arrow) was detected using the purified Pab.

Further Information

Additional Names:
Ectonucleoside triphosphate diphosphohydrolase 8, E-NTPDase 8, NTPDase 8, NTPDase8, ENTPD8
Application Note:
For WB starting dilution is: 1:1000
Background:
ENTPD8 is canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. It is ectonucleoside NTPDases catalyze the hydrolyzis of gamma-and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. ENTPD8 has activity toward ATP, ADP, UTP and UDP, but not toward AMP.
Background References:
  • Munkonda, M.N., et al. Biochem. Pharmacol. 74(10):1524-1534(2007)
  • Fausther, M., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 292 (3), G785-G795 (2007)
  • Knowles, A.F., et al. Biochemistry 45(23):7323-7333(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ENTPD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the C-terminal region of human ENTPD8.
NCBI Gene ID #:
377841
NCBI Official Name:
Ectonucleoside triphosphate diphosphohydrolase 8
NCBI Official Symbol:
ENTPD8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
Q5MY95
Protein GI Number:
158705943
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q5MY95
User NOte:
Optimal dilutions for each application to be determined by the researcher.