SORBS1 Antibody
| Code | Size | Price |
|---|
| PSI-55-343-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Hamster
- Human
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sorbin and SH3 domain-containing protein 1, Ponsin, SH3 domain protein 5, SH3P12, c-Cbl-associated protein, CAP, SORBS1 (HGNC:14565)
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010) Gehmlich, K., et al. Eur. J. Cell Biol. 89(5):351-364(2010) Yamada, Y., et al. Hypertens. Res. 32(5):325-331(2009) Fernow, I., et al. BMC Cell Biol. 10, 80 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SORBS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 866-892 amino acids from the Central region of human SORBS1.
NCBI Gene ID #:
10580
NCBI Official Name:
Sorbin and SH3 domain-containing protein 1
NCBI Official Symbol:
SORBS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
143 kDa
Protein Accession #:
Q9BX66
Protein GI Number:
317373504
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9BX66
User NOte:
Optimal dilutions for each application to be determined by the researcher.