DACH1 Antibody

ProSci
Product Code: PSI-59-360
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-360-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse lung tissue lysates (35ug/lane).

Western blot analysis in mouse lung tissue lysates (35ug/lane).

Further Information

Additional Names:
Dachshund homolog 1, Dach1, DACH1, DACH
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
  • Zhou, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(15):6864-6869(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DACH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human DACH1.
NCBI Gene ID #:
1602
NCBI Official Name:
Dachshund homolog 1
NCBI Official Symbol:
DACH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q9UI36
Protein GI Number:
519668677
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q9UI36
User NOte:
Optimal dilutions for each application to be determined by the researcher.