BRWD2 Antibody

ProSci
Product Code: PSI-62-018
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-018-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the detected BRWD2 protein (arrow).
2 / 2
Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the detected BRWD2 protein (arrow).
Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Further Information

Additional Names:
WD repeat-containing protein 11, Bromodomain and WD repeat-containing protein 2, WD repeat-containing protein 15, WDR11, BRWD2, KIAA1351, WDR15
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
Background References:
  • Katoh, M., et al. Int. J. Mol. Med. 11(5):579-583(2003)
  • Katoh, M., et al. Int. J. Oncol. 22(5):1155-1159(2003)
  • Chernova, O.B., et al. Oncogene 20(38):5378-5392(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BRWD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-572 amino acids from the Central region of human BRWD2.
NCBI Gene ID #:
55717
NCBI Official Name:
WD repeat-containing protein 11
NCBI Official Symbol:
WDR11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
137 kDa
Protein Accession #:
Q9BZH6
Protein GI Number:
17368715
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q9BZH6
User NOte:
Optimal dilutions for each application to be determined by the researcher.