CASC4 Antibody
| Code | Size | Price |
|---|
| PSI-55-230-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The increased expression level of this gene is associated
with HER-2/neu proto-oncogene overexpression. Amplification and
resulting overexpression of this proto-oncogene are found in
approximately 30% of human breast and 20% of human ovarian cancers.
Further characterization of the product of this gene may yield
insight into the fundamental biology and pathogenetic effects of
HER-2/neu overexpression in human breast and ovarian cancer cells.
Alternatively spliced variants encoding different isoforms have
been identified for this gene.
Background References:
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
- Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
- Sato, T., et al. Onkologie 26(3):268-271(2003)
- Scheer, M., et al. Mund Kiefer Gesichtschir 7(3):138-145(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.
NCBI Gene ID #:
113201
NCBI Official Name:
Protein CASC4
NCBI Official Symbol:
CASC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
Q6P4E1
Protein GI Number:
74737334
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q6P4E1
User NOte:
Optimal dilutions for each application to be determined by the researcher.