Maspin Antibody

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ProSci
Product Code: PSI-56-219
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-219-400ul400ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from Hela cell line,using Maspin Antibody. was diluted at 1:1000 at each lane
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Maspin Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis of lysate from Hela cell line,using Maspin Antibody. was diluted at 1:1000 at each lane
Maspin Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Documents

Further Information

Additional Names:
Serpin B5, Maspin, Peptidase inhibitor 5, PI-5, SERPINB5, PI5
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For IF starting dilution is: 1:10~50
Background:
SERPINB5 is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Background References:
  • Kim, J., et al. Tumour Biol. 31(5):471-476(2010)
  • Juengel, E., et al. WorldUrol 28(4):465-471(2010)
  • Besgen, P., et al. J. Immunol. 184(9):5392-5402(2010)
  • Fung, C.L., et al. Histopathology 56(3):319-330(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Maspin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human Maspin.
NCBI Gene ID #:
5268
NCBI Official Name:
Serpin B5
NCBI Official Symbol:
SERPINB5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
P36952
Protein GI Number:
229462757
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
P36952
User NOte:
Optimal dilutions for each application to be determined by the researcher.